Clinical Studies on Topical Product
Three clinical studies using prototype topical gel and cream formulations of AUS-131 have been conducted to confirm its dermal safety and potential benefits. Preclinical studies reported in the literature support potential benefits due to the compound’s antiandrogen activity, antioxidant activity, its ability to induce collagen synthesis, and its ability to prevent sunburn-induced damage to the skin.
The three clinical studies conducted by Ausio included a human repeat insult patch test (HRIPT) to assess irritation and sensitization potential, an antiaging study, and an antiblemish study. The results from these studies demonstrate the safety of the topical formulation and potential use as an antiaging and antiblemish agent.